Background Many common neurological disorders are associated with advancing chronological age, but their association with biological age (BA) remains poorly understood. Methods We studied 325 870 ...

Correspondence to: Dr J M Wardlaw Division of Clinical Neurosciences, Western General Hospital, Crewe Rd, Edinburgh EH4 2XU UK; joanna.wardlawed.ac.uk ...

Correspondence to: Professor P G E Kennedy Department of Neurology, University of Glasgow, Institute of Neurological Sciences, Southern General Hospital, Glasgow G51 4TF, UK; p.g.kennedyclinmed.gla.ac ...

Department of Neurosurgery, University of Mississippi Medical Center, Jackson, Mississippi, USA Dr J Zhang, Department of Neurosurgery, University of Mississippi Medical Center, 2500 N State Street, ...

Background Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common monogenic form of stroke and is associated with early-onset stroke ...

Correspondence to Dr Ya Miao, Department of Geriatrics, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China; nning-my{at}163.com; Prof Qihao Guo, Department of Geriatrics ...

Background The Global Burden of Disease Study (GBD) produces prevalence estimates for ‘idiopathic epilepsy’ (ie, of unknown aetiology) and ‘secondary epilepsy’ (ie, with known aetiology) but does not ...

Until recently, pathophysiological models, diagnosis and care of Alzheimer’s disease have been strikingly uncoupled. The dominant pathophysiological theory was the canonical amyloid hypothesis (cAH), ...

Antithrombotic therapy is a key element of secondary prevention in patients who have had an ischaemic stroke or transient ischaemic attack. However, its use in clinical practice is not always ...

Background It remains imperative to discover the time course that cardiovascular risk factors influence neurodegeneration in ...