Both Dr. Lolis and Mamina Turegano, MD, a dermatologist, internist, and dermatopathologist in Metairie, Louisiana, are big fans of this cult-classic serum because it contains a powerful and patented blend of vitamins C, E, and ferulic acid, which works hard to correct discoloration and target the signs of aging, like fine lines and wrinkles.

We polled dermatologists for their best serums for mature skin, and then put the formulas to the test. Our top picks suit a range from skin types and budgets, from brands like Olay, SkinCeuticals, and Estee Lauder.

Serums for mature skin often contain ingredients that can be irritating if you introduce them too quickly, like retinol and alpha hydroxyl acids (or AHAs), Dr. Sawaya says. If you