News Medical5 日
Phenotyping a TDP-43 model for ALS drug discovery
The rNLS8 model is a twofold transgenic model in which human TDP-43 expression is suppressed by doxycycline (Dox) and has a ...
News Medical5 日
Characterizing the mouse spared nerve injury model
This study evaluated behavioral, biomarker, and imaging readouts in the mouse spared nerve injury (SNI) model of neuropathic ...
eLife3 日
Rab10 inactivation promotes AMPAR insertion and spine enlargement during long-term potentiation
Among these sensors, we further focused on the spatiotemporal dynamics of Rab10 and Rab4 activity during sLTP. We found that postsynaptic stimulation leads to the persistent inactivation of Rab10 and ...