San Francisco wide receiver Deebo Samuel is averaging a career-low 3.4 catches per game this season, and he caught just one ...

The San Francisco 49ers are preparing for their Week 13 contest against the Buffalo Bills on Sunday at Highmark Stadium in ...

They have a tough game in Buffalo on Sunday night. A loss would further complicate their path to the postseason.So how is ...

This is a crucial week for the San Francisco 49ers. After Thanksgiving, they travel to face the Buffalo Bills on Sunday Night ...

San Francisco 49ers defensive end Nick Bosa missed Wednesday's practice as the team began preparations for Sunday's game ...

The San Francisco 49ers are preparing for their Week 13 contest against the Buffalo Bills on Sunday at Highmark Stadium in ...

The 49ers are welcoming Brock Purdy back to practice today after shoulder soreness kept him out of Sunday's loss at ...

The San Francisco 49ers have officially opened linebacker Dre Greenlaw's 21-day practice window, giving the team until ...

After the San Francisco 49ers' crushing 38-10 defeat to the Green Bay Packers on Sunday, Eric Branch of the San Francisco ...

Christian McCaffrey rarely has been taken off the field since returning from an eight-game absence due to bilateral Achilles ...

There seems to be a clear point in the season when 49ers linebacker Fred Warner dropped off from being a strong contender for ...

"We're just going to keep chopping wood," said running back Christian McCaffrey, as more 49ers stars grapple with ...