While the Raspberry Pi has very good support for an I2C bus, a lot of very cool chips – including the in system programmer for just about every ATtiny and ATmega microcontroller – use an SPI bus.

the Raspberry Pi 4 has six SPI controllers, six I2C controllers, and six UARTs – all on its 40-pin header. You can’t make use of all of these at once, but with up to four different connections ...