“We decided to include the use of laxatives, enemas or suppositories in the criteria for constipation, because it is a confounding factor that might mask true constipation. To compensate for ...

[15] The availability of a suppository that stimulates bowel movements without the risk of passage of large liquid stools, water retention or mucosal damage may represent an interesting ...

sequential study of outpatients with chronic functional constipation. Each patient received two suppositories of identical appearance, containing active drug or placebo. The sequence of active ...