The main classes of antibiotics and key drugs are listed below - however there are hundreds of antibiotics and this list is by no means exhaustive. Penicillin was the first antibiotic to be discovered ...

Since the 1980s very few antibiotics have been approved. One of the reasons is that there is not enough investment in the ...

No new classes of antibiotics have been invented for decades. In fact, all the antibiotics brought to the market in the past 30 years have been variations on existing drugs discovered by 1984.

Antibiotics are one of the most common classes of drugs today, and many of the complex surgeries that are now routinely done around the world have been made possible by these important drugs [1].

The protocol focuses on discovering structural classes of antibiotics but can be generally applied to other small molecules. It remains unclear whether rRNA modifications can be naturally altered ...

Traditionally, antibiotics have come from natural sources, for instance penicillin, or are modified to achieve broad-spectrum activity. Using a so-called ‘lock and key’ mechanism at the ...

Certain Gram-positive bacteria, including meticillin-resistant Staphylococcus aureus, vancomycin-resistant enterococci, and quinolone-resistant Streptococcus pneumoniae have achieved the status of ...

But of the 26 antibiotics targeting priority pathogens, most are derivates of existing antibiotic classes. Only seven meet one of the WHO's innovation criteria (absence of known cross-resistance, new ...

They can also end up in the environment and stay there. Some bacteria are resistant to multiple classes of antibiotics. They are referred to as multidrug resistant bacteria or “superbugs”. An ...

Certain Gram-positive bacteria, including meticillin-resistant Staphylococcus aureus, vancomycin-resistant enterococci, and quinolone-resistant Streptococcus pneumoniae have achieved the status of ...

A new analysis of US hospital data has found that hospital-wide use of certain classes of antibiotics is linked to increases in hospital-associated Clostridioides difficile infection (HA CDI). C ...

Metagenomic studies of soil environments identified novel and known genes that mediate resistance to different classes of antibiotics, including soil from remote locations with no known exposure ...